Dr Sally L. Gras

Qualifications
PhD (Cambridge University UK), BEng (1st class Hon) (Uni Melb), BSc (1st class Hon) (Uni Melb)
Position
Associate
Phone Number
61 3 8344 6281
Fax Number
61 3 8344 4153
Email
Department

Chemical & Biomolecular Engineering

Group
Gras Research Group
Office Location
Rm 3.08, Bldg 165 and the Bio21 Molecular Science and Biotechnology Institute

Sally Gras

Research Interests

Nano and Biomolecular Engineering

  • Nanostructured Materials
  • Tailored Biomaterials and Emulsions
  • Nano-diagnostics, nano-toxicology, nano-therapeutics
  • Fermentation processes and scale-up

Professional Affiliations

  • Member of the Cambridge Australia Trust (Victoria)
  • Member of the Australasian Society for Biomaterials
  • Member of Australian Research Council Nanotechnology Network

Honours/Awards

  • Victoria Fellowship, Business Victoria, 2009.
  • Australian-French Association for Science and Technology Fellowship, 2009.
  • Selected by The Australian Academy of Technological Sciences for Young Scientists Exchange to China, 2009.
  • Selected for Universitas 21 Faculty Leadership Program, University of Virginia, U.S.A., 2007.
  • Selby Research Award, Selby Scientific Foundation, 2006
  • The Australian Academy of Science Grant for Collaborative Research in the U.K., 2006
  • Early Career Researcher Scheme, Melbourne University, 2006
  • Delegate at the 44th Annual International Achievement Summit, New York, 2005
  • Biovision.Nxt Fellowship for future biotechnology leaders, World Life Sciences Forum, Lyon, 2005
  • Gates Cambridge Scholarship from the Bill and Melinda Gates Foundation 2003-2005
  • Chemical Engineering Design Prize, University of Melbourne, 2002
  • Bruce Knox Honours Prize, School of Botany, University of Melbourne, 2000
  • Hexima Ltd. (Biotechnology) Honours Scholarship , 2000
  • Howitt Natural History and Philosophy Scholarship, Australia, 2000-2002
  • Comalco Women in Engineering Scholarship, Australia, 1996-2000
  • Gowrie HMAS Cerberus Foundation Scholarship, Australia, 1996-2000

Professional Experience

  • 2006: Lecturer Metabolic Engineering and Laboratory Group Head, the Bio21 Molecular Science and Biotechnology Institute
  • 2003-2006: Gates Research Scholar, Cavendish Laboratory, The University of Cambridge, U.K.
  • 2002: Polymer chemistry research assistant, Chemical Engineering Department, University of Melbourne
  • 2001: Fluid mechanics research assistant, Chemical Engineering Department, University of Melbourne
  • 2000 – 2001: Recombinant protein production Hexima Ltd., Melbourne, Australia
  • 2000: Protein research assistant, The Walter and Eliza Institute of Medical Research (Undergraduates Research Opportunities Program), Australia
  • 1998: Plant biotechnology internship, Australian National University
  • 1998: Process optimization for mineral processing, Boyne Island Smelters Ltd., Gladstone, Australia
  • 1997: Process Engineer, Comalco Smelting Ltd., Australia

Selected Publications

Scholarly Book Chapters

Gras S.L., Surface and solution based assembly of amyloid fibrils for biomedical and nanotechnology applications, Advances in Chemical Engineering, 35: 161-206, 2009, Invited Chapter.

Refereed Journal Articles

Ong L., Dagastine R.R., Kentish S.E., Gras S.L., The Effect of Milk Processing on the Microstructure of the Milk Fat Globule and Rennet Induced Gel Observed Using Confocal Laser Scanning Microscopy, Journal of Food Science, accepted 14th of December 2009.

Gosling A., Stevens G.W., Barber A., Kentish S.E., Gras S.L., Recent advances refining galactooligosaccharide production from lactose, Food Chemistry, 121(2): 307-318, 2010.

Mosse W.K.J, Koppens M.L., Gras S.L., Ducker W., Complexity in Nanoparticle assembly and Function Obtained by Direct-Grafted Peptides, Langmuir, 26(2): 1013-1018, 2010.

Gosling A, Alftren J, Stevens GW, Barber A, Kentish SE, Gras S.L., Facile Pretreatment of Bacilius circulans beta-Galactosidase Increases the Yield of Galactosyl Oligosaccharides in Milk and Lactose Reaction Systems, Journal of Agricultural and Food Chemistry, 57 (24): 11507-11574, 2009.

Pham Chi L. L., Leong S.L., Ali F.E., Kenche V. B., Hill A.F., Gras S.L., Barnham K. J., Cappai R, Dopamine and the Dopamine Oxidation Product 5,6-Dihydroxylindole Promote Distinct On-Pathway and Off-Pathway Aggregation of alpha-Synuclein in a pH-Dependent Manner, Journal of Molecular Biology, 387(3): 771-785, 2009.

Han Y., Gras S.L., Forde G. M., Binding Properties of Peptidic Affinity Ligands for Plasmid DNA Capture and Detection AIChE Journal, 55(2): 505-515, 2009.

Garvey M., Gras S.L., Meehan S., Meade S., Carver J.A., Gerrard J.A., Protein nanofibres of defined morphology prepared from mixtures of crude crystallins, International Journal of Nanotechnology, 6(3-4): 258-273, 2009.

Mosse W.K.J, Koppens M.L., Thomas R. Gengenbach T.R., Scanlon D.B., Gras S.L., Ducker W.A., Peptides grafted from solids for the control of interfacial properties, Langmuir, 25(3): 1488-1494, 2009.

Gras S.L., Squires A.M., Devlin G.L., Horton M.A., Dobson C.M., MacPhee C.E., Functionalised amyloid fibrils for roles in cell adhesion, Biomaterials, 29(11): 1553-1562, 2008.

Gras S.L., Protein misfolding: a route to new nanomaterials, Advanced Powder Technology, 18(6): 699-705, 2007. Invited paper.

Gras S.L., Mahmud T., Rosengarten G., Mitchell A., Kalantar-zadeh K., Intelligent control of surface hydrophobicity, ChemPhysChem, 8(14): 2036-2050, 2007.

Gras S.L., Amyloid fibrils: from disease to design, Australian Journal of Chemistry, 60(5): 333-342, 2007, Special Research Front in Bionanochemistry. Invited review.

Squires A.M., Devlin G.L., Gras S.L., Tickler A.K., MacPhee C.E., Dobson C.M., X-ray scattering study of the effect of hydration on the cross-beta spine of amyloid fibrils, Journal of the American Chemical Society, 128(36): 11738-9, 2006.

Devlin G.L., Knowles T.P.J., Squires A.M., McCammon M.G., Gras S.L., Nilsson M.R., Robinson C.V., Welland M.E., Dobson C.M., MacPhee C.E., The Component Polypeptide Chains of Bovine Insulin Nucleate or Inhibit the Aggregation of the Parent Protein in a Conformation Dependent Manner, Journal of Molecular Biology, 360(2): 497-509, 2006.

Thorn D.C, Meehan S., Sunde M., Rekas A., Gras S.L., MacPhee C.E., Dobson C.M., Wilson, M.R., and Carver J.A., Amyloid Fibril Formation by Bovine Milk kappa-casein and Its Inhibition by the Molecular Chaperones alpha(S)- and beta-Casein, Biochemistry, 44:17027-17036, 2005.

Refereed Conference Papers

Gras S.L., Squires A.M., Dobson C.M., MacPhee C.E., Functionalised amyloid fibrils for bionanotechnology, IEEE Proceedings of ICONN 2006, Brisbane, Australia, 214-216.

Mahmud T., Wlodarski W., Mitchell A., Gras S., Trinchi A., Kalantar-zadeh K., Electrochemical Release of Immobilized IgG Protein. in Functional Materials for Chemical and Biochemical Sensors, edited by E. Comini, P-I. Gouma, V. Guidi, X-D. Zhang (Mater. Res. Soc. Symp. Proc. Volume 1010E, Warrendale, PA, 2007), 1010-V06-01.